This book provides a solid foundation in basic biochemistry and the essential role of medical biochemistry in understanding health and disease. It helps students connect molecular events with the human body's structure and function in both health and illness.Adopting the Competency-Based Medical Education (CBME) curriculum, it integrates medical biochemistry with premedical subjects and other medical disciplines, facilitating a comprehensive understanding of various medical concepts for the MBBS students.It introduces the concept of Early Clinical Exposure (ECE), aligning with the latest curriculum adopted by National Medical Commission (NMC). It includes case studies with questions and answers, offering a practical approach to learning medical biochemistry. It aims to equip the medical students with the knowledge needed for safe and effective work in a biochemistry laboratory from day one.